Thursday, May 10, 2007

HPV linked to throat cancer

The Human Papiloma Virus, a leading cause of cervical cancer, is believed now to be a cause of throat cancer.

The study, involving 100 people with throat cancer and 200 without it, found that those infected with the human papillomavirus were 32 times as likely to develop one form of oral cancer than those free of the virus. Although previous research had indicated HPV caused oral cancer, the new study is the first to definitively establish the link, researchers said.

"It makes it absolutely clear that oral HPV infection is a risk factor," said Maura L. Gillison, an assistant professor of oncology and epidemiology at the Johns Hopkins Medical Institutions in Baltimore, who led the study published in the New England Journal of Medicine.

The findings could help explain why rates of oral cancer have been increasing in recent years, particularly among younger people and those who are not smokers or heavy drinkers, which had long been the primary at-risk groups, experts said.

"There's been a kind of sea change in the last 10 years in who we're seeing with these cancers," Gillison said. "It makes sense with some changes we've seen in sexual behavior."
Scientists add that it will take more than one study to make a definitive link between oral sex-acquired HPV and cancers of the mouth and throat.

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